Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968069 | 0.84 | MAPK1 (0.38) | MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL30967987 | 0.81 | PTAFR (0.36) | RAB9AMEN1KMT2A | |
| SCHEMBL31065785 | 0.75 | USP30 (0.39) | MEN1KMT2AADAM17 | |
| SCHEMBL30968109 | 0.75 | USP30 (0.39) | MEN1KMT2AADAM17 | |
| SCHEMBL30967972 | 0.74 | DHODH (0.37) | MAPT | |
| SCHEMBL22878631 | 0.72 | TSHR (0.52) | MAPTMEN1KMT2A | |
| SCHEMBL30968023 | 0.72 | SLC22A12 (0.36) | MEN1HCRTR1KMT2AKDM4E | |
| SCHEMBL30251661 | 0.70 | LMNA (0.62) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL2884817 | 0.70 | LMNA (0.62) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL21407909 | 0.69 | TSHR (0.47) | NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |