Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968132 | 0.88 | PTAFR (0.35) | PTAFROPRM1OPRD1HRH3ADRA2A | |
| SCHEMBL30968042 | 0.88 | PTAFR (0.35) | PTAFROPRM1OPRD1HRH3ADRA2A | |
| SCHEMBL30968100 | 0.88 | PTAFR (0.35) | PTAFROPRM1OPRD1HRH3ADRA2A | |
| SCHEMBL31065785 | 0.81 | USP30 (0.39) | PTAFRMEN1KMT2A | |
| SCHEMBL30968109 | 0.81 | USP30 (0.39) | PTAFRMEN1KMT2A | |
| SCHEMBL30968016 | 0.81 | NPC1 (0.40) | MEN1KMT2ARAB9A | |
| SCHEMBL30968105 | 0.79 | POLB (0.32) | OPRM1OPRD1TLR9TLR8TLR7 | |
| SCHEMBL30968093 | 0.77 | HCRTR1 (0.34) | PTAFRTLR9TLR8TLR7GPR142 | |
| SCHEMBL31065780 | 0.76 | PLD3 (0.32) | GPR142 | |
| SCHEMBL31065783 | 0.76 | PLD3 (0.32) | GPR142 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |