Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968047 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTHPGDNPSR1 | |
| SCHEMBL30968031 | 0.93 | ALDH1A1 (0.53) | ALDH1A1LMNAHTTHPGDNPSR1 | |
| SCHEMBL633936 | 0.83 | NAMPT (0.61) | ALDH1A1LMNAHTTNAMPTMEN1 | |
| SCHEMBL13868569 | 0.83 | NAMPT (0.61) | ALDH1A1LMNAHTTNAMPTMEN1 | |
| SCHEMBL29167802 | 0.83 | NAMPT (0.61) | ALDH1A1LMNAHTTNAMPTMEN1 | |
| SCHEMBL1559634 | 0.77 | MEN1 (0.74) | ALDH1A1LMNAHTTHPGDNPSR1 | |
| SCHEMBL4661487 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTHPGDNPSR1 | |
| SCHEMBL364174 | 0.77 | NPC1 (0.62) | NAMPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL30968107 | 0.75 | HPGD (0.59) | ALDH1A1LMNAHTTHPGDNPSR1 | |
| Water SCHEMBL30838095 | 0.75 | NPC1 (0.60) | NAMPTMEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |