Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.52 |
| ▸ | USP28 | Q96RU2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC14A1 | Q13336 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722607 | 1.00 | IKBKB (0.52) | IKBKBUSP28MEN1KMT2AMAPT | |
| SCHEMBL20722662 | 0.82 | MAPT (0.54) | IKBKBMAPTNPC1RAB9AKDM4E | |
| SCHEMBL30968554 | 0.82 | MAPT (0.54) | IKBKBMAPTNPC1RAB9AKDM4E | |
| SCHEMBL22957512 | 0.81 | IKBKB (0.52) | IKBKBUSP28MEN1KMT2AMAPT | |
| SCHEMBL22957304 | 0.81 | IKBKB (0.78) | IKBKBUSP28MEN1KMT2AMAPT | |
| SCHEMBL22957259 | 0.81 | USP28 (0.49) | IKBKBUSP28MEN1KMT2AMAPT | |
| SCHEMBL20731176 | 0.76 | IKBKB (0.38) | IKBKBUSP28MAPTUSP25 | |
| SCHEMBL23938084 | 0.73 | IKBKB (0.43) | IKBKBUSP28MAPTUSP25LIMK1 | |
| SCHEMBL20722623 | 0.73 | MEN1 (0.50) | IKBKBUSP28MEN1KMT2AUSP25 | |
| SCHEMBL3836628 | 0.71 | LIMK1 (0.77) | IKBKBMEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |