Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722662 | 1.00 | MAPT (0.54) | MAPTKDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL7846025 | 0.84 | IKBKB (0.72) | MAPTKDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL7848765 | 0.84 | MAPT (0.55) | MAPTKDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL31167190 | 0.83 | MAPT (0.54) | MAPTKDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL7837105 | 0.83 | MAPT (0.54) | MAPTKDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL31167168 | 0.83 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL19212108 | 0.83 | KDM4E (0.51) | MAPTKDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL30968405 | 0.82 | IKBKB (0.52) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL20722607 | 0.82 | IKBKB (0.52) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL16504884 | 0.78 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1SMN1; SMN2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978521-A | Preparation method and application of fused ring compound | 江苏普莱医药生物技术有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |