Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968490 | 0.80 | PARP1 (0.36) | PARP1NR1H2NR1H3 | |
| SCHEMBL28052467 | 0.78 | TACR1 (0.40) | TACR1PARP1NR1H2HTR2AHTR2C | |
| SCHEMBL30968426 | 0.75 | TACR1 (0.33) | TACR1PARP1NR1H2HTR2AHTR2C | |
| SCHEMBL20722675 | 0.74 | ALDH1A1 (0.40) | NR1H2LMNA | |
| SCHEMBL30061826 | 0.74 | ALDH1A1 (0.40) | NR1H2LMNA | |
| SCHEMBL20732152 | 0.74 | ALDH1A1 (0.40) | NR1H2LMNA | |
| SCHEMBL30968467 | 0.73 | TACR1 (0.36) | TACR1PARP1HTR2AHTR2CHTR2B | |
| SCHEMBL30502301 | 0.73 | HTR2C (0.44) | TACR1PARP1NR1H2HTR2AHTR2C | |
| SCHEMBL13647340 | 0.72 | TACR1 (0.59) | TACR1PARP1HTR2AHTR2CHTR2B | |
| SCHEMBL5333905 | 0.72 | HTR2C (0.47) | PARP1NR1H2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |