Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30502301 | 0.84 | HTR2C (0.44) | TACR1PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL4564195 | 0.84 | RIPK1 (0.48) | LMNATSHR | |
| SCHEMBL30968467 | 0.82 | TACR1 (0.36) | TACR1PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL5827279 | 0.82 | HTR2C (0.43) | TACR1PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL13647340 | 0.81 | TACR1 (0.59) | TACR1PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL30873752 | 0.81 | TACR1 (0.43) | TACR1PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL5333905 | 0.81 | HTR2C (0.47) | PARP1HTR2CHTR2BHTR2ANR1H2 | |
| SCHEMBL31437077 | 0.79 | ALDH1A1 (0.43) | TACR1LMNA | |
| SCHEMBL30775551 | 0.79 | ALOX5AP (0.36) | TACR1PARP1HTR2CHTR2BHTR2A | |
| SCHEMBL30442305 | 0.79 | PARP1 (0.40) | TACR1PARP1HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666545-B | As the heterocycle Pyrazolopyrimidine analogs of JAK inhibitor | CELLZOME LTD. (GB) | 2016-04-06 | — | — | CN | disclosed |