Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968404 | 0.89 | CA1 (0.43) | CA1CA2ACHEHDAC8CTSL | |
| SCHEMBL30968458 | 0.83 | CA1 (0.41) | CA1CA2ACHECTSLCTSB | |
| SCHEMBL30968476 | 0.82 | CA1 (0.41) | CA1CA2ACHEHDAC8CTSL | |
| SCHEMBL30968528 | 0.81 | CA1 (0.40) | CA1CA2ACHECTSLCTSB | |
| SCHEMBL30968419 | 0.79 | OPRK1 (0.36) | ACHE | |
| SCHEMBL30059971 | 0.74 | CA1 (0.49) | CA1CA2ACHEHDAC8CTSL | |
| SCHEMBL20722755 | 0.74 | CA1 (0.49) | CA1CA2ACHEHDAC8CTSL | |
| SCHEMBL30089090 | 0.74 | HTR2C (0.43) | CTSLCTSBALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9490334 | 0.70 | CA1 (0.73) | CA1CA2ACHEHDAC8CTSL | |
| SCHEMBL30968555 | 0.70 | KDM1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |