Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968476 | 0.93 | CA1 (0.41) | CA1CA2ACHERORCCTSL | |
| SCHEMBL30968528 | 0.92 | CA1 (0.40) | CA1CA2ACHERORCCTSL | |
| SCHEMBL30968404 | 0.87 | CA1 (0.43) | CA1CA2ACHERORCCTSL | |
| SCHEMBL30968437 | 0.83 | CA1 (0.45) | CA1CA2ACHERORCCTSL | |
| SCHEMBL30968556 | 0.79 | DPP4 (0.32) | DPP4KDM1A | |
| SCHEMBL30968408 | 0.79 | HRH3 (0.33) | DPP4PARP1 | |
| SCHEMBL30062004 | 0.78 | ACHE (0.47) | CA1CA2ACHERORCCTSL | |
| SCHEMBL20722620 | 0.78 | ACHE (0.47) | CA1CA2ACHERORCCTSL | |
| SCHEMBL30968530 | 0.78 | CA1 (0.45) | CA1CA2ACHERORCCTSL | |
| SCHEMBL30968474 | 0.77 | CA1 (0.44) | CA1CA2ACHERORCCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |