Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968505 | 0.87 | PARP1 (0.38) | PARP1NPC1RAB9AUCHL1USP30 | |
| SCHEMBL7374803 | 0.78 | PARP1 (0.40) | PARP1UCHL1USP30ALDH1A1NR1H2 | |
| SCHEMBL30627201 | 0.78 | PARP1 (0.40) | PARP1ALDH1A1MC4RMC5RMAPT | |
| SCHEMBL29757596 | 0.78 | GPR119 (0.45) | PARP1 | |
| SCHEMBL28412863 | 0.78 | GPR119 (0.45) | PARP1 | |
| SCHEMBL30493824 | 0.78 | PARP1 (0.38) | PARP1UCHL1USP30NR1H2 | |
| SCHEMBL30968489 | 0.77 | CA1 (0.45) | ALDH1A1MAPT | |
| SCHEMBL30931161 | 0.77 | PARP1 (0.41) | PARP1ALDH1A1MC4RMC5RMAPT | |
| SCHEMBL28562416 | 0.76 | PARP1 (0.43) | PARP1NPC1RAB9AALDH1A1NR1H2 | |
| SCHEMBL29773951 | 0.76 | GPR119 (0.45) | PARP1USP30ALDH1A1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |