Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685502 | 1.00 | KDM4E (0.38) | KDM4ELMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7716540 | 0.76 | SMN1; SMN2 (0.49) | KDM4ELMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16685569 | 0.75 | HPGD (0.58) | KDM4ENPSR1ALDH1A1SMN1; SMN2GFER | |
| SCHEMBL16696186 | 0.73 | HPGD (0.34) | KDM4ELMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9218365 | 0.71 | PDK1 (0.56) | KDM4EALDH1A1SMN1; SMN2GFERCYP1A2 | |
| SCHEMBL30422981 | 0.71 | CYP1A2 (0.75) | KDM4ELMNAALDH1A1SMN1; SMN2GFER | |
| SCHEMBL422527 | 0.71 | CYP1A2 (0.75) | KDM4ELMNAALDH1A1SMN1; SMN2GFER | |
| SCHEMBL14676613 | 0.70 | MAOB (0.52) | KDM4ELMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10974016 | 0.69 | ALDH1A1 (0.41) | KDM4ELMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16696187 | 0.69 | HASPIN (0.39) | LMNANPSR1ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118059093-A | Inhibitors of short chain dehydrogenase activity for the treatment of fibrosis | 卡斯西部储备大学 | 2024-05-24 | — | — | CN | disclosed |