Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154983 | 0.91 | TNIK (0.49) | HTR7KDM4EHRH3EPHX2 | |
| SCHEMBL30969317 | 0.90 | TNIK (0.51) | KDM4EEPHX2 | |
| SCHEMBL3234486 | 0.87 | KDM4E (0.61) | HTR7KDM4ENAMPTMAPT | |
| SCHEMBL4620651 | 0.82 | HRH3 (0.64) | HTR7KDM4EPRSS1HRH3F2 | |
| SCHEMBL4786207 | 0.81 | EPHX2 (0.61) | CHRNA7KCNH2NAMPTHRH3MAPT | |
| SCHEMBL3988708 | 0.80 | BACE1 (0.50) | BACE1CACNA1BHRH3 | |
| SCHEMBL30969324 | 0.79 | HDAC6 (0.52) | HTR7KDM4ENAMPTMAPT | |
| Oxalic Acid SCHEMBL4564705 | 0.79 | HRH3 (0.60) | HTR7KDM4EPRSS1CACNA1BHRH3 | |
| SCHEMBL4622234 | 0.79 | HRH3 (0.62) | HTR7PRSS1HRH3F2PRSS2 | |
| Hydrochloric Acid SCHEMBL4808510 | 0.78 | BACE1 (0.49) | BACE1CACNA1BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642766-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | disclosed |