Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | NAMPT | P43490 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788314 | 0.96 | EPHX2 (0.60) | EPHX2CHRNA7KCNH2NAMPTHTR3A | |
| SCHEMBL4786227 | 0.91 | EPHX2 (0.59) | EPHX2CHRNA7KCNH2NAMPTMAPT | |
| SCHEMBL4788021 | 0.88 | EPHX2 (0.64) | EPHX2CHRNA7KCNH2MAPT | |
| SCHEMBL4787450 | 0.87 | EPHX2 (0.63) | EPHX2CHRNA7KCNH2NAMPTMAPT | |
| SCHEMBL4788178 | 0.87 | EPHX2 (0.58) | EPHX2CHRNA7KCNH2HTR3A | |
| SCHEMBL4787642 | 0.85 | EPHX2 (0.63) | EPHX2CHRNA7KCNH2HTR3A | |
| SCHEMBL4786193 | 0.84 | EPHX2 (0.56) | EPHX2MAPTHTR3AHRH3CNR1 | |
| SCHEMBL4788976 | 0.83 | POLB (0.54) | EPHX2CHRNA7KCNH2MAPTHTR3A | |
| SCHEMBL4786204 | 0.82 | EPHX2 (0.60) | EPHX2CHRNA7KCNH2MAPT | |
| SCHEMBL30969280 | 0.81 | HTR7 (0.53) | EPHX2CHRNA7KCNH2NAMPTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |