Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154983 | 0.88 | TNIK (0.49) | CNR1ALDH1A1POLBHTR7KDM4E | |
| SCHEMBL30969317 | 0.87 | TNIK (0.51) | CNR1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL3222256 | 0.84 | EPHX2 (0.54) | CNR1ALDH1A1POLBLMNAKDM4E | |
| SCHEMBL31606858 | 0.80 | LMNA (0.54) | HDAC6HDAC2HDAC8CNR1ALDH1A1 | |
| SCHEMBL30969280 | 0.79 | HTR7 (0.53) | MAPTNAMPTHTR7KDM4E | |
| SCHEMBL30969294 | 0.78 | POLB (0.70) | ALDH1A1POLBLMNATP53KDM4E | |
| SCHEMBL14924426 | 0.78 | MAPT (0.55) | HDAC6HDAC2HDAC8CNR1ALDH1A1 | |
| SCHEMBL8245902 | 0.78 | ALDH1A1 (0.51) | CNR1ALDH1A1LMNAMAPTNAMPT | |
| SCHEMBL4699834 | 0.77 | SIGMAR1 (0.50) | HDAC6HDAC2HDAC8ALDH1A1HTR7 | |
| SCHEMBL3234486 | 0.76 | KDM4E (0.61) | ALDH1A1LMNAMAPTNAMPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642766-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | disclosed |