Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 3/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 8/20 | 0.36 |
| ▸ | NNMT | P40261 | 3/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19645365 | 0.86 | SIRT6 (0.67) | SIRT6BACE1NNMTCHEK2ADORA3 | |
| SCHEMBL30826969 | 0.78 | SIRT6 (0.62) | SIRT6BACE1NNMTCHEK2ADORA3 | |
| SCHEMBL2793061 | 0.75 | SIRT6 (0.47) | SIRT6ADRA1A | |
| SCHEMBL1935667 | 0.75 | SIRT6 (0.50) | SIRT6BACE1 | |
| SCHEMBL19645364 | 0.75 | SIRT6 (0.68) | SIRT6BACE1NNMTADORA3TSHR | |
| SCHEMBL3102878 | 0.74 | SIRT6 (1.00) | SIRT6BACE1NNMTADORA3TSHR | |
| SCHEMBL15476644 | 0.72 | SIRT6 (0.62) | SIRT6BACE1NNMTADORA3TSHR | |
| Formic Acid SCHEMBL2593977 | 0.71 | SIRT6 (0.53) | SIRT6TMEM97SIGMAR1BACE1NNMT | |
| SCHEMBL2482296 | 0.70 | SIRT6 (0.45) | SIRT6OXTRAVPR1AAVPR2BACE1 | |
| SCHEMBL2516931 | 0.70 | SIRT6 (0.45) | SIRT6OXTRAVPR1AAVPR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642766-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | disclosed |