Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097035 | 1.00 | CA1 (0.50) | CA1CA2PLA2G4BTP53TSHR | |
| SCHEMBL28577854 | 0.86 | TP53 (0.49) | CA1CA2PLA2G4BTP53TSHR | |
| SCHEMBL9225196 | 0.83 | TP53 (0.54) | CA1CA2PLA2G4BTP53TSHR | |
| SCHEMBL9225206 | 0.83 | TP53 (0.54) | CA1CA2PLA2G4BTP53TSHR | |
| SCHEMBL6925756 | 0.81 | TP53 (0.59) | PLA2G4BTP53TSHRKMT2AALDH1A1 | |
| SCHEMBL8378126 | 0.81 | TP53 (0.59) | PLA2G4BTP53TSHRKMT2AALDH1A1 | |
| SCHEMBL8378127 | 0.81 | TP53 (0.59) | PLA2G4BTP53TSHRKMT2AALDH1A1 | |
| SCHEMBL28731497 | 0.81 | CYP19A1 (0.41) | TP53KMT2AHTT | |
| SCHEMBL23220822 | 0.80 | RECQL (0.36) | RXRARXRBPARP10KMT2AALDH1A1 | |
| SCHEMBL9330072 | 0.80 | RARB (0.57) | PLA2G4BTP53TSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799243-B2 | Shape memory main-chain smectic-C elastomers | UNIVERSITY OF CONNECTICUT (US) | 2010-09-21 | — | — | US | disclosed |
| US-7601274-B2 | addition-condensation copolymer is formed from hydrosilylation, comprising a liquid crystalline diene, crosslinking agent tetrakis(vinyldimethylsiloxy)silane and hydride-terminated polydimethylsiloxane; implantable medical device, intraocular lens, contact lens; reversible shape changes | THE UNIVERSITY OF CONNECTICUT (US) | 2009-10-13 | — | — | US | disclosed |
| US-20090240075-A1 | SHAPE MEMORY MAIN-CHAIN SMECTIC-C ELASTOMERS | MATHER PATRICK T | 2009-09-24 | — | — | US | disclosed |
| WO-2005103201-A1 | SHAPE MEMORY MAIN-CHAIN SMECTIC-C ELASTOMERS | UNIVERSITY OF CONNECTICUT (US) | 2005-11-03 | — | — | WO | disclosed |
| US-20050242325-A1 | Shape memory main-chain smectic-C elastomers | CONNECTICUT, UNIVERSITY OF | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240075-A1 | SHAPE MEMORY MAIN-CHAIN SMECTIC-C ELASTOMERS | HBS1L, SMCHD1, SMC2 | CA1 270/4885CA2 1221/4885PLA2G4B 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.