Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195125 | 1.00 | IDO1 (0.53) | IDO1DAOPDE2ARXRARXRB | |
| SCHEMBL29492592 | 0.85 | IDO1 (0.53) | IDO1DAOPDE2ARXRARXRB | |
| SCHEMBL952712 | 0.85 | IDO1 (0.53) | IDO1DAOPDE2ARXRARXRB | |
| SCHEMBL4961852 | 0.84 | MRGPRX4 (0.47) | IDO1DAOPDE2ARXRARXRB | |
| SCHEMBL6902387 | 0.84 | RXRA (0.40) | IDO1PDE2ARXRARXRBRXRG | |
| SCHEMBL30858773 | 0.84 | MRGPRX4 (0.47) | IDO1DAOPDE2ARXRARXRB | |
| SCHEMBL28196892 | 0.83 | IDO1 (0.54) | IDO1DAOPDE2ASLC6A4SLC6A2 | |
| SCHEMBL5929043 | 0.81 | RXRA (0.51) | IDO1DAORXRARXRBRXRG | |
| SCHEMBL11156664 | 0.81 | RXRA (0.38) | IDO1DAORXRARXRBRXRG | |
| SCHEMBL31454497 | 0.81 | RXRA (0.38) | IDO1DAORXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115068468-B | Carboxylic aromatic amides as bradykinin B1 receptor antagonists | 拜耳制药股份公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-115137726-B | Carboxylic aromatic amides as bradykinin B1 receptor antagonists | 拜耳制药股份公司 | 2024-08-13 | — | — | CN | disclosed |