Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970519 | 0.84 | IDO1 (0.53) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL195125 | 0.84 | IDO1 (0.53) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL25786471 | 0.80 | DAO (0.43) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL31454497 | 0.80 | RXRA (0.38) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL11156664 | 0.80 | RXRA (0.38) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL5929043 | 0.80 | RXRA (0.51) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL29492592 | 0.80 | IDO1 (0.53) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL952712 | 0.80 | IDO1 (0.53) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL24108423 | 0.79 | ALDH1A1 (0.42) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL4961852 | 0.79 | MRGPRX4 (0.47) | RXRARXRBRXRGIDO1POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | claimed |
| EP-1431279-A2 | Fluoride containing aromatic compounds | Bayer Chemicals AG (DE) | 2004-06-23 | — | — | EP | claimed |
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
| EP-1431279-A2 | Fluoride containing aromatic compounds | Bayer Chemicals AG (DE) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171864-A1 | Fluorinated aromatics | AFF1, AFF2, AFF4 | RXRA 181/4885RXRB 363/4885RXRG 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.