Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970529 | 0.84 | TP53 (0.35) | HPGDLMNATP53MAPTGAA | |
| SCHEMBL30970541 | 0.81 | HPGD (0.44) | HPGDKMT2AMEN1IGF1RL3MBTL1 | |
| SCHEMBL23553375 | 0.76 | MAPT (0.40) | HPGDKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL30970523 | 0.73 | TP53 (0.34) | HPGDLMNATP53MAPTGAA | |
| SCHEMBL23552964 | 0.71 | LMNA (0.49) | LMNATP53MAPT | |
| SCHEMBL23552969 | 0.71 | LMNA (0.49) | LMNATP53MAPT | |
| SCHEMBL23553851 | 0.71 | MAPT (0.43) | LMNATP53MAPT | |
| SCHEMBL23530643 | 0.71 | MAPT (0.43) | LMNATP53MAPT | |
| SCHEMBL29674361 | 0.71 | MAPT (0.43) | LMNATP53MAPT | |
| SCHEMBL29674376 | 0.71 | MAPT (0.43) | LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140968-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD AND USE THEREFOR | 广州市联瑞制药有限公司 | 2024-07-04 | — | — | WO | disclosed |