Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970523 | 0.86 | TP53 (0.34) | TP53MAPTLMNASHMT2KDM4E | |
| SCHEMBL31051691 | 0.84 | SHMT2 (0.37) | TP53MAPTLMNASHMT2ALDH1A1 | |
| SCHEMBL30970533 | 0.84 | WDR5 (0.34) | TP53MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL31051694 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MMP13GPR84 | |
| SCHEMBL31521635 | 0.76 | LMNA (0.32) | TP53MAPTLMNA | |
| SCHEMBL31521631 | 0.76 | LMNA (0.32) | TP53MAPTLMNA | |
| SCHEMBL23552925 | 0.75 | MAPT (0.51) | TP53MAPTLMNASHMT2THRB | |
| SCHEMBL23530967 | 0.75 | MAPT (0.51) | TP53MAPTLMNASHMT2THRB | |
| SCHEMBL23530533 | 0.75 | MAPT (0.51) | TP53MAPTLMNASHMT2THRB | |
| SCHEMBL23530585 | 0.74 | SHMT2 (0.44) | TP53MAPTLMNASHMT2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140968-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD AND USE THEREFOR | 广州市联瑞制药有限公司 | 2024-07-04 | — | — | WO | disclosed |