Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30812401 | 0.75 | AURKA (0.34) | AURKATTKAURKBINCENP | |
| SCHEMBL30970559 | 0.73 | AURKA (0.31) | AURKATTKAURKBINCENP | |
| SCHEMBL30970590 | 0.71 | EGFR (0.35) | AURKATTKAURKBINCENP | |
| SCHEMBL15212500 | 0.71 | DPYD (0.40) | AURKATTKAURKBINCENP | |
| SCHEMBL30970585 | 0.71 | PIK3CD (0.33) | AURKATTKAURKBINCENP | |
| SCHEMBL30970557 | 0.71 | AURKA (0.32) | AURKATTKAURKBINCENP | |
| SCHEMBL30970555 | 0.67 | CSNK2A1 (0.38) | — | |
| SCHEMBL30970589 | 0.66 | ADRB2 (0.40) | — | |
| SCHEMBL30970593 | 0.65 | LRRK2 (0.37) | — | |
| SCHEMBL30970612 | 0.65 | POLB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957226-A | Heterocyclic compounds as SOS1 inhibitors and uses thereof | 南京再明医药有限公司 | 2024-04-30 | — | — | CN | disclosed |