Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.34 |
| ▸ | POLR1A | O95602 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102531 | 0.95 | PPARD (0.36) | TACR1POLR1ASCN7AKCNH2SCN5A | |
| SCHEMBL3107963 | 0.95 | PPARD (0.35) | TACR1POLR1ASCN7AKCNH2SCN5A | |
| SCHEMBL3111704 | 0.94 | ELANE (0.35) | POLR1ASCN7AKCNH2SCN5ASCN9A | |
| SCHEMBL3115589 | 0.90 | POLR1A (0.34) | POLR1APPARDS1PR1S1PR3ELANE | |
| SCHEMBL870579 | 0.89 | MEN1 (0.36) | TACR1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL3115119 | 0.86 | MEN1 (0.36) | TACR1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL3105544 | 0.86 | FAP (0.35) | TACR1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL3107706 | 0.85 | TACR1 (0.38) | TACR1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL10072325 | 0.85 | GPR52 (0.37) | — | |
| SCHEMBL869923 | 0.85 | P2RX1 (0.36) | TACR1P2RX1P2RX3P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222618-A1 | NAPTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. du Pont de Nemours and Company (US) | 2017-09-27 | — | — | EP | claimed |
| US-20140113943-A9 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2014-04-24 | — | — | US | claimed |
| US-20130217736-A1 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | DU PONT (US) | 2013-08-22 | — | — | US | claimed |
| US-20100254959-A1 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-07 | — | — | US | claimed |
| EP-3222618-B1 | NAPTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | DU PONT (US) | 2020-09-09 | — | — | EP | disclosed |
| EP-3222618-A1 | NAPTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. du Pont de Nemours and Company (US) | 2017-09-27 | — | — | EP | disclosed |
| US-20140113943-A9 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2014-04-24 | — | — | US | disclosed |
| US-20130217736-A1 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | DU PONT (US) | 2013-08-22 | — | — | US | disclosed |
| US-8410153-B2 | Naphthalene isoxazoline invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-02 | — | — | US | disclosed |
| US-20100254959-A1 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100254959-A1 | NAPHTHALENE ISOXAZOLINE INVERTEBRATE PEST CONTROL AGENTS | C1S, C1R, C9 | TACR1 983/4885POLR1A 3360/4885SCN7A 297/4885 |
| US-20130217736-A1 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | C1S, C1R, C9 | TACR1 983/4885POLR1A 3360/4885SCN7A 297/4885 |
| US-20140113943-A9 | Naphthalene Isoxazoline Invertebrate Pest Control Agents | C1S, C1R, C9 | TACR1 983/4885POLR1A 3360/4885SCN7A 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.