Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.51 |
| ▸ | BLK | P51451 | 7/20 | 0.50 |
| ▸ | LYN | P07948 | 3/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20450661 | 0.81 | CYP2C9 (0.48) | BTK | |
| SCHEMBL18764531 | 0.81 | CYP2C9 (0.48) | BTK | |
| SCHEMBL31437335 | 0.81 | CYP2C9 (0.48) | BTK | |
| SCHEMBL23952719 | 0.78 | TNKS (0.55) | — | |
| SCHEMBL30970924 | 0.78 | EGFR (0.56) | BTKLYNLCK | |
| SCHEMBL18425302 | 0.75 | CYP3A4 (0.53) | — | |
| SCHEMBL6215045 | 0.75 | TNKS (0.60) | — | |
| SCHEMBL16987454 | 0.75 | BTK (0.50) | BTKBLKLYNLCK | |
| SCHEMBL16987455 | 0.75 | BTK (0.50) | BTKBLKLYNLCK | |
| SCHEMBL13081097 | 0.75 | DRD2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637726-A1 | DRUG FORMULATIONS OF (R)-1-(1-ACRYLOYLPIPERIDIN-3-YL)-4-AMINO-3-(4- PHENOXYPHENYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE | Principia Biopharma Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137604-A1 | DRUG FORMULATIONS OF (R)-L-(L-ACRYLOYLPIPERIDIN-3-YL)-4-AMINO-3-(4- PHENOXYPHENYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE | GENZYME CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |