Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 19/20 | 0.70 |
| ▸ | THRB | P10828 | 19/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.63 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.63 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924045 | 0.82 | THRA (1.00) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL23245130 | 0.81 | THRA (0.68) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL24032592 | 0.79 | THRA (0.81) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL23441631 | 0.78 | THRA (0.80) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL16919814 | 0.78 | THRA (0.68) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL2925261 | 0.77 | THRA (0.62) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL30820657 | 0.77 | THRA (0.62) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL23420796 | 0.77 | THRA (0.78) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL13907340 | 0.77 | THRB (1.00) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL2926289 | 0.77 | THRB (0.67) | THRATHRBCYP2C9UGT1A1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045551-B | Compound serving as thyroid hormone beta receptor agonist and application thereof | 广东东阳光药业股份有限公司 | 2024-07-09 | — | — | CN | disclosed |