Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | F11 | P03951 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971293 | 0.92 | GRM2 (0.34) | GRM2XDHCFTRF11KDM4E | |
| SCHEMBL30971048 | 0.91 | GRM2 (0.35) | GRM2XDHCFTRF11KDM4E | |
| SCHEMBL30971037 | 0.89 | PKMYT1 (0.38) | GRM2XDHF11PKMYT1MEN1 | |
| SCHEMBL27388054 | 0.89 | PKMYT1 (0.38) | GRM2XDHF11PKMYT1MEN1 | |
| SCHEMBL30971091 | 0.88 | GRM2 (0.37) | GRM2XDHCFTRF11KDM4E | |
| SCHEMBL30971164 | 0.87 | XDH (0.41) | GRM2XDH | |
| SCHEMBL30971276 | 0.87 | GRM2 (0.37) | GRM2PKMYT1 | |
| SCHEMBL30971282 | 0.83 | GRM2 (0.35) | GRM2XDHPKMYT1 | |
| SCHEMBL30971053 | 0.83 | ALDH1A1 (0.37) | F11KDM4ETNFHPGDKMT2A | |
| SCHEMBL30971108 | 0.80 | PKMYT1 (0.36) | GRM2PKMYT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |