Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.44 |
| ▸ | GRK2 | P25098 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 13/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | PRKX | P51817 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27387956 | 1.00 | PKMYT1 (0.44) | PKMYT1GRK2GRM2TNK2PLK4 | |
| SCHEMBL27387961 | 0.89 | PKMYT1 (0.36) | PKMYT1GRK2FGFR1MAPTALDH1A1 | |
| SCHEMBL30971143 | 0.89 | PKMYT1 (0.36) | PKMYT1GRK2FGFR1MAPTALDH1A1 | |
| SCHEMBL27387965 | 0.89 | PKMYT1 (0.36) | PKMYT1GRK2GRM2TNK2FGFR1 | |
| SCHEMBL30971043 | 0.86 | GRM2 (0.42) | PKMYT1GRK2GRM2 | |
| SCHEMBL27388126 | 0.81 | PKMYT1 (0.44) | PKMYT1GRK2TNK2PLK4CHEK1 | |
| SCHEMBL27397482 | 0.76 | GRM2 (0.63) | GRM2ALDH1A1 | |
| SCHEMBL30971258 | 0.76 | UCHL3 (0.34) | GRM2MAPTALDH1A1 | |
| SCHEMBL30971134 | 0.75 | GRM2 (0.42) | PKMYT1GRM2LCK | |
| SCHEMBL27387959 | 0.75 | GRM2 (0.42) | PKMYT1GRM2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |