Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 13/20 | 0.42 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971258 | 0.90 | UCHL3 (0.34) | GRM2KDM4ELMNA | |
| SCHEMBL30971103 | 0.88 | CYP1A2 (0.35) | GRM2 | |
| SCHEMBL27387956 | 0.86 | PKMYT1 (0.44) | GRM2PKMYT1GRK2 | |
| SCHEMBL30971122 | 0.86 | PKMYT1 (0.44) | GRM2PKMYT1GRK2 | |
| SCHEMBL30971268 | 0.81 | ACACB (0.38) | PKMYT1KDM4E | |
| SCHEMBL30971088 | 0.79 | ADORA3 (0.41) | KDM4E | |
| SCHEMBL27401560 | 0.78 | GRM2 (0.58) | GRM2KDM4E | |
| SCHEMBL30971182 | 0.77 | GRM2 (0.41) | GRM2PKMYT1 | |
| SCHEMBL30971143 | 0.76 | PKMYT1 (0.36) | PKMYT1KDM4EGRK2 | |
| SCHEMBL27387961 | 0.76 | PKMYT1 (0.36) | PKMYT1KDM4EGRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |