Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 13/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971070 | 0.86 | GRM2 (0.39) | GRM2PKMYT1HSD17B10SYK | |
| SCHEMBL30971089 | 0.84 | GRM2 (0.39) | GRM2PKMYT1 | |
| SCHEMBL30971335 | 0.81 | GRM2 (0.38) | GRM2PKMYT1SYK | |
| SCHEMBL30971221 | 0.81 | PKMYT1 (0.36) | GRM2PKMYT1NQO2PIM1PIM3 | |
| SCHEMBL30971210 | 0.80 | DYRK1A (0.36) | CYP19A1NQO2HSD17B10 | |
| SCHEMBL27401560 | 0.79 | GRM2 (0.58) | GRM2 | |
| SCHEMBL30971254 | 0.78 | PKMYT1 (0.36) | GRM2PKMYT1NQO2PIM1PIM3 | |
| SCHEMBL30971267 | 0.78 | NQO2 (0.41) | GRM2PKMYT1NQO2PIM1PIM3 | |
| SCHEMBL30971160 | 0.78 | DYRK1A (0.41) | GRM2PKMYT1PIM1PIM3PIM2 | |
| SCHEMBL30971213 | 0.77 | GRM2 (0.38) | GRM2PKMYT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |