Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 18/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27397482 | 0.85 | GRM2 (0.63) | GRM2ALDH1A1 | |
| SCHEMBL13075989 | 0.79 | ALOX15 (0.77) | GRM2ALOX15KDM4EALDH1A1 | |
| SCHEMBL30971158 | 0.79 | GRM2 (0.39) | GRM2 | |
| SCHEMBL30971070 | 0.79 | GRM2 (0.39) | GRM2 | |
| SCHEMBL27398361 | 0.79 | GRM2 (0.64) | GRM2ALDH1A1 | |
| SCHEMBL30971043 | 0.78 | GRM2 (0.42) | GRM2KDM4E | |
| SCHEMBL27941539 | 0.77 | GRM2 (0.69) | GRM2ALDH1A1 | |
| SCHEMBL30971089 | 0.77 | GRM2 (0.39) | GRM2 | |
| SCHEMBL30971182 | 0.77 | GRM2 (0.41) | GRM2 | |
| SCHEMBL30905482 | 0.76 | PKMYT1 (0.47) | ALOX15KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622967-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |