Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 3/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971078 | 0.88 | PKMYT1 (0.39) | PKMYT1PIM1PIM2PIM3GRM2 | |
| SCHEMBL27388049 | 0.88 | PKMYT1 (0.39) | PKMYT1PIM1PIM2PIM3GRM2 | |
| SCHEMBL30971221 | 0.85 | PKMYT1 (0.36) | DYRK1AKDM4EMEN1KMT2APKMYT1 | |
| SCHEMBL30971091 | 0.82 | GRM2 (0.37) | KDM4EPKMYT1SMN1; SMN2GRM2 | |
| SCHEMBL30971031 | 0.78 | GRM2 (0.36) | HSD17B10NPSR1KDM4EHPGDMEN1 | |
| SCHEMBL30971158 | 0.78 | GRM2 (0.39) | HSD17B10PKMYT1PIM1PIM2PIM3 | |
| SCHEMBL30971048 | 0.77 | GRM2 (0.35) | BRAFHSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL30971254 | 0.77 | PKMYT1 (0.36) | MEN1KMT2APKMYT1PIM1PIM2 | |
| SCHEMBL30971267 | 0.77 | NQO2 (0.41) | HPGDPKMYT1PIM1PIM2PIM3 | |
| SCHEMBL30971070 | 0.76 | GRM2 (0.39) | HSD17B10HPGDPKMYT1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |