SCHEMBL30972167

SCHEMBL30972167

CC(N=Cc1ccccc1O)C(N)=Cc1ccccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
MAPT P10636 4/20 0.45
KDM4E B2RXH2 3/20 0.45
GAA P10253 3/20 0.45
ALOX15 P16050 2/20 0.45
HPGD P15428 2/20 0.45
USP2 O75604 1/20 0.45
POLB P06746 1/20 0.45
ALOX12 P18054 1/20 0.45
RECQL P46063 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CA12 O43570 6/20 0.44
CA2 P00918 6/20 0.44
CA9 Q16790 5/20 0.44
SIRT2 Q8IXJ6 1/20 0.44
RAB9A P51151 3/20 0.41
KMT2A Q03164 3/20 0.41
NPC1 O15118 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4669668 0.79 KDM4E (0.42) ALDH1A1MAPTKDM4EGAAALOX15
SCHEMBL4669664 0.79 KDM4E (0.42) ALDH1A1MAPTKDM4EGAAALOX15
SCHEMBL6865789 0.79 KDM4E (0.42) ALDH1A1MAPTKDM4EGAAALOX15
SCHEMBL28544831 0.79 ALDH1A1 (0.51) ALDH1A1MAPTKDM4EGAAALOX15
SCHEMBL2493458 0.78 ALDH1A1 (0.54) ALDH1A1MAPTKDM4EGAAALOX15
SCHEMBL21055888 0.78 ALDH1A1 (0.54) ALDH1A1MAPTKDM4EGAAALOX15
SCHEMBL10336703 0.78 ALDH1A1 (0.54) ALDH1A1MAPTKDM4EGAAALOX15
SCHEMBL501627 0.75 CA12 (0.50) ALDH1A1MAPTKDM4EGAAALOX15
SCHEMBL29483209 0.75 CA12 (0.50) ALDH1A1MAPTKDM4EGAAALOX15
SCHEMBL501630 0.75 CA12 (0.50) ALDH1A1MAPTKDM4EGAAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751380-A Polyamine heterocyclic compound, preparation method and application thereof, and polyamine heterocyclic compound combined solution 大连理工大学 2025-04-04 CN disclosed
CN-114105812-B Method for synthesizing N, N' -bis-salicylidene-1, 2-propanediamine by using chloropropene byproduct 1, 2-dichloropropane 中国石油化工股份有限公司 2024-07-05 CN disclosed