SCHEMBL4669664

SCHEMBL4669664

CC(N)/C(N)=C\c1ccccc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.42
GAA P10253 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
CA12 O43570 6/20 0.41
CA2 P00918 6/20 0.41
CA9 Q16790 5/20 0.41
SIRT2 Q8IXJ6 1/20 0.41
MAPT P10636 4/20 0.39
ALOX15 P16050 2/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
RECQL P46063 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6865789 1.00 KDM4E (0.42) KDM4EGAAL3MBTL1TRIM24TRIM33
SCHEMBL4669668 1.00 KDM4E (0.42) KDM4EGAAL3MBTL1TRIM24TRIM33
SCHEMBL3690222 0.80 MAPT (0.40) KDM4EGAAL3MBTL1TRIM24TRIM33
SCHEMBL3690223 0.80 MAPT (0.40) KDM4EGAAL3MBTL1TRIM24TRIM33
SCHEMBL3457401 0.80 TRIM24 (0.45) KDM4EGAAL3MBTL1TRIM24TRIM33
SCHEMBL30972167 0.79 ALDH1A1 (0.46) KDM4EGAAL3MBTL1CA12CA2
SCHEMBL4775532 0.78 CA12 (0.43) KDM4EGAAL3MBTL1CA12CA2
SCHEMBL6565751 0.78 CA12 (0.40) KDM4EGAAL3MBTL1TRIM24TRIM33
SCHEMBL49775 0.77 TRPA1 (0.43) KDM4EGAAL3MBTL1TRIM24TRIM33
SCHEMBL1697046 0.77 TRPA1 (0.43) KDM4EGAAL3MBTL1TRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1934313-A1 COMPOSITION AND METHOD FOR ENHANCING THE STABILITY OF JET FUELS Nalco Company (US) 2008-06-25 EP claimed
WO-2007042887-A1 COMPOSITION AND METHOD FOR ENHANCING THE STABILITY OF JET FUELS NALCO COMPANY (US) 2007-04-19 WO claimed
EP-2748363-A1 INSULATING MATERIAL COMPRISING NONWOVEN WEBS E. I. Du Pont de Nemours and Company (US) 2014-07-02 EP disclosed
WO-2013032912-A1 INSULATING MATERIAL COMPRISING NONWOVEN WEBS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-03-07 WO disclosed