Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097799 | 0.83 | MVD (0.44) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL3103093 | 0.77 | TSHR (0.36) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL3100743 | 0.74 | USP2 (0.32) | MEN1KMT2AALOX15 | |
| SCHEMBL16376903 | 0.72 | TSHR (0.46) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL2872034 | 0.71 | TSHR (0.50) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL11741097 | 0.71 | TSHR (0.62) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL9442588 | 0.71 | TSHR (0.55) | TSHRPPARDMEN1GAACYP2C9 | |
| SCHEMBL21165829 | 0.70 | ACHE (0.36) | TSHRPPARDTDP1ACHEALOX15 | |
| SCHEMBL13407442 | 0.70 | LMNA (0.37) | TSHRCYP2C9CYP2C19TDP1ALOX15 | |
| SCHEMBL16376900 | 0.69 | TSHR (0.43) | TSHRPPARDMEN1GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |