Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 20/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30973461 | 0.74 | IL1B (0.57) | IL1BNLRP3TNF | |
| SCHEMBL30973284 | 0.70 | IL1B (0.37) | IL1BNLRP3 | |
| SCHEMBL30973542 | 0.67 | IL1B (0.56) | IL1BNLRP3TNF | |
| SCHEMBL22695045 | 0.65 | IL1B (0.61) | IL1BNLRP3TNF | |
| SCHEMBL31199651 | 0.64 | IL1B (0.57) | IL1BNLRP3TNF | |
| SCHEMBL22695042 | 0.62 | IL1B (0.57) | IL1BNLRP3TNF | |
| SCHEMBL22655138 | 0.62 | IL1B (0.57) | IL1BNLRP3TNF | |
| SCHEMBL31637350 | 0.61 | IL1B (0.47) | IL1BNLRP3TNF | |
| SCHEMBL22654806 | 0.60 | IL1B (1.00) | IL1BNLRP3TNF | |
| SCHEMBL22654980 | 0.60 | IL1B (1.00) | IL1BNLRP3TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | claimed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |