Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30973521 | 0.86 | HTR2A (0.36) | CHRM1HTR2A | |
| SCHEMBL30973550 | 0.71 | IL1B (0.51) | IL1BNLRP3 | |
| SCHEMBL30973333 | 0.70 | IL1B (0.43) | IL1BNLRP3 | |
| SCHEMBL30973530 | 0.69 | HTR2A (0.40) | CHRM1HTR2A | |
| SCHEMBL30973453 | 0.68 | CHRM1 (0.33) | CHRM1CHRM2CHRM3 | |
| SCHEMBL30973594 | 0.67 | CHRM1 (0.35) | CHRM1HTR2ACHRM2CHRM3 | |
| SCHEMBL30973501 | 0.62 | EED (0.31) | — | |
| SCHEMBL30993907 | 0.61 | IL1B (0.57) | IL1BNLRP3 | |
| SCHEMBL9342114 | 0.58 | CHRM2 (0.50) | CHRM1CHRM2CHRM3 | |
| SCHEMBL22671969 | 0.56 | IL1B (0.78) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | claimed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |