Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | RAMP3 | O60896 | 11/20 | 0.39 |
| ▸ | CALCR | P30988 | 11/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825115 | 0.97 | KEAP1 (0.41) | KEAP1RAMP3CALCREPHX2MAPK8 | |
| SCHEMBL29825278 | 0.95 | MEN1 (0.39) | KEAP1RAMP3CALCRMAPK8MAPK9 | |
| SCHEMBL29777409 | 0.91 | KEAP1 (0.41) | KEAP1EPHX2MAPK8MAPK9MAPK10 | |
| SCHEMBL30808875 | 0.90 | KEAP1 (0.44) | KEAP1RAMP3CALCREPHX2MAPK8 | |
| SCHEMBL29892053 | 0.90 | KEAP1 (0.41) | KEAP1RAMP3CALCRMAPK8MAPK9 | |
| SCHEMBL29406566 | 0.89 | KEAP1 (0.43) | KEAP1RAMP3CALCRMAPK8MAPK9 | |
| SCHEMBL29824927 | 0.89 | MAPK8 (0.42) | KEAP1EPHX2MAPK8MAPK9MAPK10 | |
| SCHEMBL31632216 | 0.89 | MEN1 (0.41) | KEAP1EPHX2MAPK8MAPK9MAPK10 | |
| SCHEMBL29689742 | 0.89 | PRCP (0.44) | EPHX2MAPK8MAPK9MAPK10 | |
| SCHEMBL29824782 | 0.88 | NMT1 (0.40) | MAPK8MAPK9MAPK10NMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | claimed |