SCHEMBL29777409

SCHEMBL29777409

N=C(N)NCCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KEAP1 Q14145 2/20 0.41
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ MAPK8 P45983 1/20 0.39
▸ MAPK9 P45984 1/20 0.39
▸ MAPK10 P53779 1/20 0.39
▸ PRCP P42785 2/20 0.38
▸ TERT O14746 1/20 0.38
▸ GNPAT O15228 1/20 0.37
▸ EPHA2 P29317 1/20 0.36
▸ EPHX2 P34913 2/20 0.35
▸ CALCRL Q16602 1/20 0.35
▸ KDM1A O60341 1/20 0.35
▸ ITGB3 P05106 1/20 0.34
▸ ITGA2B P08514 1/20 0.34
▸ DPP7 Q9UHL4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29824927 0.94 MAPK8 (0.42) KEAP1MEN1KMT2AMAPK8MAPK9
SCHEMBL29825115 0.94 KEAP1 (0.41) KEAP1MEN1KMT2AMAPK8MAPK9
SCHEMBL29689742 0.92 PRCP (0.44) MEN1KMT2AMAPK8MAPK9MAPK10
SCHEMBL29825278 0.92 MEN1 (0.39) KEAP1MEN1KMT2AMAPK8MAPK9
SCHEMBL29892053 0.92 KEAP1 (0.41) KEAP1MAPK8MAPK9MAPK10TERT
SCHEMBL30745230 0.92 MEN1 (0.41) KEAP1MEN1KMT2AMAPK8MAPK9
SCHEMBL29406566 0.92 KEAP1 (0.43) KEAP1MAPK8MAPK9MAPK10EPHA2
SCHEMBL30974053 0.91 KEAP1 (0.40) KEAP1MAPK8MAPK9MAPK10EPHX2
SCHEMBL29824782 0.90 NMT1 (0.40) MEN1KMT2AMAPK8MAPK9MAPK10
SCHEMBL29892015 0.90 KEAP1 (0.44) KEAP1MAPK8MAPK9MAPK10EPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4591934-A2 VARIANTS OF C-TYPE NATRIURETIC PEPTIDE BioMarin Pharmaceutical Inc. (US) 2025-07-30 — — EP disclosed
EP-4523749-A2 VARIANTS OF C-TYPE NATRIURETIC PEPTIDE BioMarin Pharmaceutical Inc. (US) 2025-03-19 — — EP disclosed
EP-4029512-A1 VARIANTS OF C-TYPE NATRIURETIC PEPTIDE BioMarin Pharmaceutical Inc. (US) 2022-07-20 — — EP disclosed
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