Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.57 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.57 |
| ▸ | ECE1 | P42892 | 4/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.55 |
| ▸ | ITGAL | P20701 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30052764 | 0.93 | KDM4E (0.62) | ACEOPRM1OPRD1ERAP2ECE1 | |
| SCHEMBL30605164 | 0.91 | ACE (0.59) | ACEOPRM1OPRD1ERAP2ECE1 | |
| SCHEMBL29366904 | 0.90 | ERAP2 (0.60) | ACEOPRM1OPRD1ERAP2ECE1 | |
| SCHEMBL30051470 | 0.90 | ECE1 (0.66) | ACEOPRM1OPRD1ERAP2ECE1 | |
| SCHEMBL30052858 | 0.90 | OPRM1 (0.69) | ACEOPRM1OPRD1ERAP2LTA4H | |
| SCHEMBL30974288 | 0.90 | CCKAR (0.57) | ACEOPRM1OPRD1ERAP2ECE1 | |
| SCHEMBL7422711 | 0.89 | ACE (0.68) | ACEECE1LTA4HALOX15KDM4E | |
| SCHEMBL14941216 | 0.89 | ACE (0.68) | ACEECE1LTA4HALOX15KDM4E | |
| SCHEMBL29603940 | 0.89 | ACE (0.68) | ACEECE1LTA4HALOX15KDM4E | |
| SCHEMBL29886823 | 0.88 | ERAP2 (0.58) | ACEOPRM1OPRD1ERAP2ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | disclosed |