SCHEMBL30052858

SCHEMBL30052858

N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.69
OPRD1 P41143 2/20 0.69
LTA4H P09960 1/20 0.62
ERAP1 Q9NZ08 2/20 0.59
ERAP2 Q6P179 2/20 0.59
LNPEP Q9UIQ6 1/20 0.59
ALOX15 P16050 1/20 0.59
ACE P12821 2/20 0.58
KMT2A Q03164 1/20 0.58
MME P08473 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051323 0.96 OPRM1 (0.68) OPRM1OPRD1LTA4HERAP1ERAP2
SCHEMBL30052764 0.95 KDM4E (0.62) OPRM1OPRD1ERAP2ALOX15ACE
SCHEMBL30307613 0.94 OPRD1 (0.75) OPRM1OPRD1LTA4HERAP1ERAP2
SCHEMBL30128516 0.93 OPRD1 (0.73) OPRM1OPRD1LTA4HERAP1ERAP2
SCHEMBL31038379 0.93 OPRM1 (0.66) OPRM1OPRD1LTA4HERAP1ERAP2
SCHEMBL30502977 0.92 OPRD1 (0.69) OPRM1OPRD1LTA4HERAP1ERAP2
SCHEMBL30502988 0.91 OPRM1 (0.64) OPRM1OPRD1LTA4HACE
SCHEMBL31106415 0.91 OPRD1 (0.73) OPRM1OPRD1ERAP1ERAP2LNPEP
SCHEMBL30605164 0.91 ACE (0.59) OPRM1OPRD1ERAP2ALOX15ACE
SCHEMBL30503003 0.90 OPRD1 (0.68) OPRM1OPRD1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930743-A ACE (angiotensin converting enzyme) inhibitory peptide, preparation method and application 美泰科技(青岛)股份有限公司 2025-05-06 CN claimed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
CN-121779489-A Bioactive peptide in tobacco stems, screening preparation thereof and application of bioactive peptide in tobacco stems in resisting tobacco mosaic virus 云南省烟草公司玉溪市公司 2026-04-03 CN disclosed
CN-119930743-A ACE (angiotensin converting enzyme) inhibitory peptide, preparation method and application 美泰科技(青岛)股份有限公司 2025-05-06 CN disclosed
CN-119930743-A ACE (angiotensin converting enzyme) inhibitory peptide, preparation method and application 美泰科技(青岛)股份有限公司 2025-05-06 CN disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP OPRM1 804/4885OPRD1 402/4885LTA4H 3533/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD OPRM1 2130/4885OPRD1 2937/4885LTA4H 1299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.