SCHEMBL30974329

C[C@@H](O)[C@H](NC(=O)CN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	FOLH1	Q04609	2/20	0.42

▸	NPY4R	P50391	7/20	0.40

▸	NPY5R	Q15761	6/20	0.40

▸	NPY1R	P25929	5/20	0.40

▸	NPY2R	P49146	3/20	0.40

▸	KEAP1	Q14145	1/20	0.38

▸	NOD1	Q9Y239	1/20	0.38

▸	SIRT5	Q9NXA8	2/20	0.37

▸	SIRT2	Q8IXJ6	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29485116	0.93	NPY4R (0.38)	NPY4RNPY5RNPY1RNPY2RNOD1
SCHEMBL29539785	0.92	NPY4R (0.38)	NPY4RNPY5RNPY1RNPY2RNOD1
SCHEMBL29720839	0.89	FOLH1 (0.46)	FOLH1NPY4RNPY5RNPY1RNPY2R
SCHEMBL29736322	0.88	TFPI (0.48)	—
SCHEMBL31674373	0.88	NPY4R (0.44)	FOLH1NPY4RNPY5RNPY1RNPY2R
SCHEMBL8429823	0.88	NPY5R (0.46)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL30577044	0.87	NMT2 (0.41)	NPY4RNPY5RNPY1RNPY2RSIRT5
SCHEMBL29485119	0.86	NPY4R (0.43)	FOLH1NPY4RNPY5RNPY1RNPY2R
SCHEMBL30903440	0.85	BACE1 (0.43)	NPY4RNPY5RNPY1RNPY2RKEAP1
SCHEMBL30974313	0.85	NMT1 (0.43)	FOLH1NPY4RNPY5RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024132726-A1	SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE	UNIWERSYTET GDANSKI (PL)	2024-06-27	—	—	WO	disclosed