SCHEMBL29539785

SCHEMBL29539785

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nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 10/20 0.38
▸ NPY5R Q15761 9/20 0.38
▸ NPY1R P25929 8/20 0.38
▸ NPY2R P49146 6/20 0.38
▸ SLC15A2 Q16348 1/20 0.37
▸ NOD1 Q9Y239 1/20 0.37
▸ FURIN P09958 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29485116 0.99 NPY4R (0.38) NPY4RNPY5RNPY1RNPY2RSLC15A2
SCHEMBL30577044 0.92 NMT2 (0.41) NPY4RNPY5RNPY1RNPY2R
SCHEMBL30974329 0.92 FOLH1 (0.42) NPY4RNPY5RNPY1RNPY2RNOD1
SCHEMBL29485118 0.91 FURIN (0.40) NPY4RNPY5RNPY1RNPY2RSLC15A2
SCHEMBL29485119 0.90 NPY4R (0.43) NPY4RNPY5RNPY1RNPY2RNOD1
SCHEMBL29740225 0.88 NOD1 (0.46) NPY4RNPY5RNPY1RNPY2RNOD1
SCHEMBL29540259 0.88 NOD1 (0.46) NPY4RNPY5RNPY1RNPY2RNOD1
SCHEMBL29485113 0.87 ENPEP (0.43) —
SCHEMBL29540572 0.87 NPY4R (0.39) NPY4RNPY5RNPY1RNPY2RNOD1
SCHEMBL31198207 0.87 NPY4R (0.46) NPY4RNPY5RNPY1RNPY2RNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 — — US disclosed
US-11891457-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 — — US disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891457-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R NPY4R 58/4885NPY5R 195/4885NPY1R 121/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R NPY4R 58/4885NPY5R 195/4885NPY1R 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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