Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 4/20 | 0.46 |
| ▸ | CTSD | P07339 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.42 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.40 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30974105 | 0.92 | CALCRL (0.46) | CALCRLCTSDBACE1APLNRRAMP1 | |
| SCHEMBL30974436 | 0.89 | CALCRL (0.52) | CALCRLNMUR2NMUR1 | |
| SCHEMBL30608602 | 0.85 | NAA50 (0.48) | CALCRLAPLNRKEAP1NAA50NMUR2 | |
| SCHEMBL30608623 | 0.84 | CAPN1 (0.47) | CALCRLCTSDBACE1APLNRRAMP1 | |
| SCHEMBL30608585 | 0.84 | CAPN1 (0.47) | CALCRLCTSDBACE1APLNRRAMP1 | |
| SCHEMBL29479863 | 0.84 | NPY2R (0.52) | KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL31001017 | 0.84 | CALCRL (0.47) | CALCRLAPLNRKEAP1RAMP1NAA50 | |
| SCHEMBL30403555 | 0.83 | CALCRL (0.49) | CALCRLKEAP1RAMP1XIAP | |
| SCHEMBL8936972 | 0.83 | STAT3 (0.47) | CALCRLCTSDBACE1KEAP1NMUR2 | |
| SCHEMBL30978825 | 0.83 | BACE1 (0.50) | CTSDBACE1KEAP1NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | disclosed |