Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.64 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.64 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.64 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | REN | P00797 | 9/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | NPY1R | P25929 | 2/20 | 0.53 |
| ▸ | NPY2R | P49146 | 2/20 | 0.53 |
| ▸ | NPY4R | P50391 | 2/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.53 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.52 |
| ▸ | CALCR | P30988 | 1/20 | 0.52 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.52 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31295732 | 0.88 | MAPK8 (0.60) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL30974554 | 0.87 | C5AR1 (0.58) | KEAP1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30974286 | 0.87 | F2 (0.57) | NPY1RNPY2RNPY4RNPY5RCALCR | |
| SCHEMBL30974459 | 0.87 | C5AR1 (0.60) | KEAP1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30974458 | 0.87 | C5AR1 (0.59) | KEAP1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30974387 | 0.87 | C5AR1 (0.59) | KEAP1NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30607332 | 0.87 | MAPK8 (0.64) | MAPK8MAPK9MAPK10EPHA2KEAP1 | |
| SCHEMBL30712941 | 0.86 | MAPK8 (0.73) | MAPK8MAPK9MAPK10EPHA2KEAP1 | |
| SCHEMBL30930223 | 0.86 | OPRM1 (0.55) | MAPK8MAPK9MAPK10EPHA2REN | |
| SCHEMBL29590593 | 0.86 | OPRM1 (0.55) | MAPK8MAPK9MAPK10EPHA2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | disclosed |