SCHEMBL29590593

SCHEMBL29590593

N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 4/20 0.55
▸ OPRD1 P41143 4/20 0.55
▸ MAPK8 P45983 1/20 0.55
▸ MAPK9 P45984 1/20 0.55
▸ MAPK10 P53779 1/20 0.55
▸ EPHA2 P29317 3/20 0.54
▸ BDKRB2 P30411 1/20 0.54
▸ NMUR2 Q9GZQ4 5/20 0.54
▸ NMUR1 Q9HB89 5/20 0.54
▸ KDM1A O60341 1/20 0.49
▸ REN P00797 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30930223 1.00 OPRM1 (0.55) OPRM1OPRD1MAPK8MAPK9MAPK10
SCHEMBL22649131 0.96 BDKRB2 (0.57) OPRM1OPRD1MAPK8MAPK9MAPK10
SCHEMBL30973973 0.91 MAPK8 (0.43) OPRM1OPRD1MAPK8MAPK9MAPK10
SCHEMBL38655084 0.88 BDKRB2 (0.43) OPRM1OPRD1MAPK8MAPK9MAPK10
SCHEMBL29824994 0.88 MAPK8 (0.47) MAPK8MAPK9MAPK10EPHA2BDKRB2
Bradykinin SCHEMBL7949679 0.87 BDKRB2 (0.67) OPRM1OPRD1EPHA2BDKRB2NMUR2
Bradykinin SCHEMBL7949684 0.87 BDKRB2 (0.67) OPRM1OPRD1EPHA2BDKRB2NMUR2
SCHEMBL30672572 0.87 BDKRB2 (0.72) OPRM1OPRD1EPHA2BDKRB2NMUR2
SCHEMBL30974521 0.86 MAPK8 (0.64) MAPK8MAPK9MAPK10EPHA2NMUR2
SCHEMBL30782709 0.86 OPRM1 (0.62) OPRM1OPRD1EPHA2BDKRB2NMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618102-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited (GB) 2026-05-05 — — US disclosed
US-20220112547-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12618102-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions POLM, POLR1A, POLR1E OPRM1 4101/4885OPRD1 4566/4885MAPK8 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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