Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29269008 | 0.98 | FAAH (0.40) | FAAHPTGDR2CNR2CES1KDM4C | |
| Lithium Ion SCHEMBL25213639 | 0.87 | FAAH (0.37) | FAAHPTGDR2CNR2CES1VNN1 | |
| SCHEMBL30474046 | 0.83 | GABRA1 (0.40) | FAAHPTGDR2CNR2MAPTFASN | |
| SCHEMBL25210663 | 0.83 | GABRA1 (0.40) | FAAHPTGDR2CNR2MAPTFASN | |
| Lithium SCHEMBL30975815 | 0.81 | PTGDR2 (0.41) | FAAHPTGDR2CES1KDM4CVNN1 | |
| Lithium SCHEMBL30975782 | 0.80 | DHODH (0.42) | FAAH | |
| SCHEMBL29268905 | 0.79 | PTPN1 (0.39) | PTGDR2CNR2KDM4CFASNSCD | |
| SCHEMBL29268904 | 0.78 | PTGDR2 (0.41) | FAAHPTGDR2CES1KDM4CVNN1 | |
| SCHEMBL25675636 | 0.77 | USP30 (0.46) | USP30 | |
| SCHEMBL29268908 | 0.77 | DHODH (0.42) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302422-A | Substituted N-cyanopyrrolidines having activity as USP30 inhibitors | 特殊治疗有限公司 | 2024-07-05 | — | — | CN | disclosed |