Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319354 | 0.79 | KDM4E (0.55) | KDM4ETP53ALOX5DAOMPO | |
| SCHEMBL30976381 | 0.78 | MPO (0.44) | KDM4ECA1CA2ACHEDAO | |
| SCHEMBL17559152 | 0.76 | KDM4E (0.56) | KDM4ETP53ALDH1A1LMNAPOLB | |
| SCHEMBL1101962 | 0.75 | KDM4E (1.00) | KDM4ETP53ALOX5ALDH1A1LMNA | |
| SCHEMBL31091767 | 0.75 | KDM4E (1.00) | KDM4ETP53ALOX5ALDH1A1LMNA | |
| SCHEMBL22721901 | 0.75 | TSHR (0.67) | KDM4ECA1CA2ACHEPOLB | |
| SCHEMBL8834687 | 0.73 | KDM4E (0.53) | KDM4ETP53CA1CA2ACHE | |
| SCHEMBL15680203 | 0.72 | KDM4E (0.55) | KDM4ETP53CA1CA2ALOX5 | |
| SCHEMBL30976328 | 0.71 | MPO (0.44) | KDM4ECA1CA2ACHEDAO | |
| SCHEMBL3110885 | 0.70 | DAO (0.69) | KDM4EDAOALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |