Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976328 | 0.94 | MPO (0.44) | MPOCA1CA2ACHEPLK1 | |
| SCHEMBL29900257 | 0.81 | PARP1 (0.44) | GLSALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL30976299 | 0.78 | KDM4E (0.59) | MPOCA1CA2ACHEDAO | |
| SCHEMBL10484937 | 0.78 | GLS (0.62) | GLSALDH1A1KDM4ELMNA | |
| SCHEMBL22721901 | 0.74 | TSHR (0.67) | CA1CA2ACHEKDM4EPOLB | |
| SCHEMBL28960848 | 0.74 | PARP1 (0.40) | GLSALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL28960486 | 0.70 | MEN1 (0.46) | CA1CA2ACHEL3MBTL1DAO | |
| SCHEMBL22721888 | 0.68 | TSHR (0.67) | KDM4EPOLBMAPT | |
| SCHEMBL30880198 | 0.68 | TSHR (0.67) | KDM4EPOLBMAPT | |
| SCHEMBL30976429 | 0.68 | ALDH1A1 (0.42) | GLSDAOALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |