Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 6/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 11/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13158037 | 1.00 | SLC6A7 (0.50) | SLC6A7HCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL6371790 | 0.91 | SLC6A7 (0.50) | SLC6A7HCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL1258219 | 0.91 | SLC6A7 (0.50) | SLC6A7HCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL2399599 | 0.86 | SLC6A7 (0.53) | SLC6A7HCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL6371729 | 0.86 | SLC6A7 (0.53) | SLC6A7HCRTR1HCRTR2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL4557356 | 0.85 | SLC6A7 (0.62) | SLC6A7ALDH1A1TSHRHSP90AB1SLC6A3 | |
| Hydrochloric Acid SCHEMBL4557354 | 0.85 | SLC6A7 (0.62) | SLC6A7ALDH1A1TSHRHSP90AB1SLC6A3 | |
| SCHEMBL6371749 | 0.80 | SLC6A7 (0.51) | SLC6A7HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL1257221 | 0.80 | SLC6A7 (0.51) | SLC6A7HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL3093054 | 0.79 | HRH4 (0.44) | SLC6A7HCRTR1HCRTR2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399455-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | ACKR3, CCR5, CXCR2 | SLC6A7 938/4885HCRTR1 359/4885HCRTR2 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.