Meglutol

Meglutol

SCHEMBL30976339

CC(O)(CC(=O)O)CC(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.75
CHRM1 P11229 1/20 0.75
TBXA2R P21731 1/20 0.75
ADRA1A P35348 1/20 0.75
TSHR P16473 2/20 0.50
CYP2C19 P33261 2/20 0.50
HIF1A Q16665 2/20 0.50
CYP2D6 P10635 1/20 0.50
ACLY P53396 3/20 0.48
ALDH1A1 P00352 2/20 0.46
CPT2 P23786 2/20 0.39
KDM4E B2RXH2 1/20 0.39
FFAR1 O14842 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TET2 Q6N021 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Meglutol SCHEMBL28443 0.87 HMGCR (1.00) HMGCRCHRM1TBXA2RADRA1ATSHR
Meglutol SCHEMBL8718194 0.87 HMGCR (1.00) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL126376 0.80 HMGCR (0.75) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL21272609 0.78 HMGCR (0.64) HMGCRCHRM1TBXA2RADRA1ATSHR
Trifluoroacetic Acid SCHEMBL2455122 0.78 ALDH1A1 (0.56) HMGCRCHRM1TBXA2RADRA1ATSHR
Meglutol SCHEMBL31372614 0.77 HMGCR (0.79) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL9907217 0.77 HMGCR (0.79) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL27601378 0.77
Citric Acid SCHEMBL3785967 0.77 ALDH1A1 (0.79) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL16005836 0.77 HMGCR (0.79) HMGCRCHRM1TBXA2RADRA1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638415-A1 BIS-ESTER AND AMIDE CATIONIC LIPIDS Sanofi Pasteur Inc. (US) 2025-10-29 EP disclosed
WO-2024133853-A1 BIS-ESTER AND AMIDE CATIONIC LIPIDS SANOFI (FR) 2024-06-27 WO disclosed