Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976361 | 0.91 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30976446 | 0.90 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30976463 | 0.84 | LMNA (0.58) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30976411 | 0.81 | TP53 (0.56) | KMT2AMEN1MAPTALDH1A1NPSR1 | |
| SCHEMBL30976292 | 0.79 | ALDH1A1 (0.52) | KMT2AMEN1MAPTALDH1A1NPSR1 | |
| SCHEMBL30976499 | 0.77 | LMNA (0.56) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30976325 | 0.75 | LMNA (0.54) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13012376 | 0.74 | SMN1; SMN2 (0.77) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1432512 | 0.73 | KMT2A (0.72) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13930739 | 0.72 | MAPT (0.78) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |